When you introduce another substance that has the ability to alter processing times, the drug could metabolize slower or faster. If the Cytochrome P450 system is unhealthy due to liver disease or other pre-existing conditions, it might not be hemp oil for dogs able to metabolize the drug at all. According to the Davis Drug Guide, there are more than 50 enzymes that process and eliminate toxins from the body. The one responsible for the metabolism of most prescription drugs is the CYP3A4 enzyme. CBD interacts with drugs the same way grapefruit does – it inhibits the metabolizing function of the Cytochrome P450.
And if you cannot take grapefruit juice with a particular drug, then you should not take CBD too. While most of the available research indicates that CBD oil is safe for human consumption, it does pose a few risks when taken in combination with certain substances.
Terpenes play a huge role in the reason essential oils smell and act the way they do, and they provide many of the natural medicinal benefits which essential oils have. Therefore, full-spectrum CBD also contains some of these benefits, for it can contain terpenes such as limonene, myrcene, pinene, and linalool, which are all very well known for their benefits. Isolated Terpenes can also be purchased if someone is looking for Cannabinoid Terpenes specifically rather than a Full Spectrum CBD oil rich in Terpenes. As mentioned above, the cons are mainly the fact that your medication(s) or drug(s) may not be processed normally in your body and can, therefore, be released within your body in irregular amounts.
Drugs that stay too long in your system can be dangerous especially if you are taking powerful painkillers such as oxycodone and fentanyl. CBD can prevent your system from metabolizing certain compounds which slows down the elimination of a drug from your body.
If these drugs are not processed by the CYP3A4 enzyme, there will be very little active compound to achieve the desired therapeutic effect. If you are taking medication together with CBD, you should consult your doctor to make sure you are consuming both products safely and effectively. The interaction between CBD and Cytochrome P450 is most prominent in anti-seizure medications designed for treating epilepsy. CBD is known to inhibit the ability of Cytochrome P450 enzymes to metabolize certain drugs, leading to a much longer processing time. If a patient is taking only one drug and the system is generally healthy, medical practitioners can easily come up with accurate dosage information.
This leads to you experiencing the unprecedented side effects of a drug, which is not altogether the most pleasant or safe. Taking CBD alongside certain medications which don’t rely on the Cytochrome P-450 enzyme system to be broken down can be quite good in the eyes of some. As they cannot be processed, the drugs will just stay in your body instead of being digested as they should. It breaks down the substances you put in your body, and turns them into simpler substances that your body actually knows how to use. According to the Department of Health, Columbia, absolute contraindications for CBD and cannabis include acute psychosis and other unstable psychiatric conditions.
Cannabidiol (CBD) has become a popular treatment for back pain and other conditions. This content is for informational and educational purposes only. Statements on this website have not been evaluated by the Food and Drug Administration. Always consult a qualified healthcare provider before beginning any nutrition, supplement, or lifestyle program.